The budget impact of implementing atrial fibrillation-screening in European countries

Author:

Eklund Michaela1ORCID,Bernfort Lars1ORCID,Appelberg Kajsa1,Engler Daniel23ORCID,Schnabel Renate B23ORCID,Martinez Carlos4,Wallenhorst Christopher4,Boriani Giuseppe5ORCID,Buckley Claire M6,Diederichsen Søren Zöga7,Svendsen Jesper Hastrup78,Montaner Joan91011,Potpara Tatjana1213ORCID,Levin Lars-Åke1ORCID,Lyth Johan1ORCID

Affiliation:

1. Unit of Healthcare Analysis, Department of Medical and Health Sciences, Linköping University , Linköping , Sweden

2. Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf , Hamburg , Germany

3. DZHK (German Center for Cardiovascular Research) , Partner Site Hamburg/Kiel/Luebeck , Germany

4. Institute for Epidemiology, Statistics and Informatics GmbH , Frankfurt , Germany

5. Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, Italy University of Modena and Reggio Emilia, Policlinico di Modena , Modena , Italy

6. School of Public Health, University College Cork , Cork , Ireland

7. Department of Cardiology, Copenhagen University Hospital – Rigshospitalet , Inge Lehmanns Vej 7, 2100 Copenhagen , Denmark

8. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Blegdamsvej 3B, 2200 Copenhagen , Denmark

9. Neurovascular Research Laboratory, Vall d’Hebron Institute of Research (VHIR) Universitat Autònoma de Barcelona , Barcelona , Spain

10. Institute de Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville

11. Department of Neurology, Hospital Universitario Virgen Macarena , Seville , Spain

12. Medical Faculty, University of Belgrade , Belgrade , Serbia

13. Cardiology Clinic, University Clinical Centre of Serbia , Belgrade , Serbia

Abstract

Abstract A budget impact analysis estimates the short-term difference between the cost of the current treatment strategy and a new treatment strategy, in this case to implement population screening for atrial fibrillation (AF). The aim of this study is to estimate the financial impact of implementing population-based AF-screening of 75-year-olds compared with the current setting of no screening from a healthcare payer perspective in eight European countries. The net budget impact of AF-screening was estimated in country-specific settings for Denmark, Germany, Ireland, Italy, Netherlands, Serbia, Spain, and Sweden. Country-specific parameters were used to allow for variations in healthcare systems and to reflect the healthcare sector in the country of interest. Similar results can be seen in all countries AF-screening incurs savings of stroke-related costs since AF treatment reduces the number of strokes. However, the increased number of detected AF and higher drug acquisition will increase the drug costs as well as the costs of physician- and control visits. The net budget impact per invited varied from €10 in Ireland to €122 in the Netherlands. The results showed the increased costs of implementing AF-screening were mainly driven by increased drug costs and screening costs. In conclusion, across Europe, though the initial cost of screening and more frequent use of oral anti-coagulants will increase the healthcare payers’ costs, introducing population screening for AF will result in savings of stroke-related costs.

Funder

European Union’s Horizon 2020 research and innovation programme

LOOP Study

Innovation Fund Denmark

Research Foundation for the Capital Region of Denmark

Danish Heart Foundation

Aalborg University Talent Management Program

Arvid Nilssons Fond

Skibsreder Per Henriksen

R og Hustrus Fond

European Union’s Horizon 2020 program

Læge Sophus Carl Emil Friis og hustru Olga Doris Friis’ Legat

European Research Council

German Center for Cardiovascular Research

German Ministry of Research and Education

German Heart Foundation

Publisher

Oxford University Press (OUP)

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