Maintaining therapeutic progress in multiple myeloma by integrating genetic and biological advances into the clinic
Author:
Affiliation:
1. Myeloma Institute, The University of Arkansas for Medical Sciences, Little Rock, AR, USA
Publisher
Informa UK Limited
Subject
Hematology
Link
https://www.tandfonline.com/doi/pdf/10.1080/17474086.2018.1489718
Reference93 articles.
1. The clinical significance of cereblon expression in multiple myeloma
2. CC-122 Degrades the Lymphoid Transcription Factor Aiolos (IKZF3) By Modulating Cereblon and Shows Clinical Activity in a Phase Ib Study of Subjects with Relapsed or Refractory Non-Hodgkin’s Lymphoma and Multiple Myeloma
3. Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
4. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
5. A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance
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Progress in the identification of gene mutations involved in multiple myeloma
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