A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Author:
Affiliation:
1. 1Celgene Corporation, 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01921
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4. Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
5. Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
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