Reduced expression of L-selectin in T-cells correlates with relative lymphocyte increase in patients with RRMS treated with natalizumab - functional implication towards PML risk-Reference-Cited by-同舟云学术

Reduced expression of L-selectin in T-cells correlates with relative lymphocyte increase in patients with RRMS treated with natalizumab - functional implication towards PML risk

Published:2020-02-12 Issue:3 Volume:42 Page:209-221
ISSN:0161-6412
Container-title:Neurological Research
language:en
Short-container-title:Neurological Research

Author:

Boziki Marina Kleopatra¹,Karapanayotides Theodoros¹,Papadopoulos Georgios¹,Lagoudaki Roza¹,Melo Pamela¹,Bakirtzis Christos¹,Nikolaidis Ioannis¹,Gounari Evdoxia²^ORCID,Tsavdaridou Vasiliki²,Skoura Lemonia²,Afrantou Theodora¹,Tatsi Theano¹,Grigoriadou Eleni¹,Polyzoidou Eleni¹,Mandoras Nikolaos¹,Giantzi Virginia¹,Kalogera - Fountzila Anna³,Ioannidis Panagiotis¹,Parissis Dimitrios¹,Pelidou Sygkliti-Henrietta¹,Zoidou Sofia¹,Grigoriadis Nikolaos¹

Affiliation:

1. 2nd Neurological University Clinic, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece

2. Laboratory of Immunology, Department of Microbiology, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece

3. Department of Radiology, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece

Publisher

Informa UK Limited

Subject

Neurology (clinical),Neurology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01616412.2020.1722913

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1. PROGRESSIVE MULTIFOCAL LEUKO-ENCEPHALOPATHY

2. Continued declining incidence and improved survival of progressive multifocal leukoencephalopathy in HIV/AIDS patients in the current era

3. Specific loss of cellular L-selectin on CD4+ T cells is associated with progressive multifocal leukoencephalopathy development during HIV infection

4. Anti–JC virus antibody levels in serum or plasma further define risk of natalizumab‐associated progressive multifocal leukoencephalopathy

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