Autophagy in the eye: from physiology to pathophysiology

Author:

Liton Paloma B.1ORCID,Boesze-Battaglia Kathleen2,Boulton Michael E.3,Boya Patricia4,Ferguson Thomas A.5,Ganley Ian G.6,Kauppinnen Anu7,Laurie Gordon W.8,Mizushima Noboru9,Morishita Hideaki910,Russo Rossella11,Sadda Jaya12,Shyam Rajalekshmy13,Sinha Debasish1415,Thompson Debra A.12,Zacks David N.12

Affiliation:

1. Departments of Ophthalmology & Pathology, Duke School of Medicine, Duke University, Durham, NC 27705, USA

2. Department of Basic and Translational Sciences, University of Pennsylvania, School of Dental Medicine, Philadelphia, PA 19104, USA

3. Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham (UAB), Birmingham, AL, USA

4. Department of Neuroscience and Movement Science. Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland

5. Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, MO 63110, USA

6. MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK

7. Faculty of Health and Sciences, School of Pharmacy, University of Eastern Finland, 70210 Kuopio, Finland

8. Departments of Cell Biology, Ophthalmology and Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA

9. Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 113-0033, Japan

10. Department of Physiology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan

11. Preclinical and Translational Pharmacology, Glaucoma Unit, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy

12. Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA

13. School of Optometry, Indiana University, Bloomington, IN 47405, USA

14. Department of Ophthalmology, Cell Biology, and Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

15. Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Funder

National Eye Institute

Research to Prevent Blindness

Grant-in-Aid for Specially Promoted Research from the Japan Society for the Promotion of Science

Grant-in-Aid for Scientific Research

Advanced Research and Development Programs for Medical Innovation

Medical Research Council

TearSolutions, Inc

Exploratory Research for Advanced Technology research funding program of the Japan Science and Technology Agency

Publisher

Informa UK Limited

Reference327 articles.

1. Autophagy in the eye: Development, degeneration, and aging;Boya P;Prog Retin Eye Res,2016

2. Autophagy in major human diseases;Klionsky DJ;EMBO J,2021

3. Diverse Cellular Roles of Autophagy;Morishita H;Annu Rev Cell Dev Biol,2019

4. - distinct molecular mechanisms handle cargoes of many sizes;Microautophagy Schuck S.;J Cell Sci,2020

5. Autophagy and the hallmarks of aging;Kaushik S;Ageing Res Rev,2021

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