Clinical Development of PROTACs
Author:
Publisher
Springer Nature Singapore
Link
https://link.springer.com/content/pdf/10.1007/978-981-97-5077-1_9
Reference52 articles.
1. Atilaw Y, Poongavanam V, Nilsson CS, Nguyen D, Giese A, Meibom D, Erdelyi M, Kihlberg J (2021) Solution conformations shed light on PROTAC cell permeability. ACS Med Chem Lett 12(1):107–114
2. Bai N, Miller S, Andrianov G, Yates M, Kirubakaran P, Karanicolas J (2021) Rationalizing PROTAC-mediated ternary complex formation using Rosetta. J Chem Inf Model 61:1368
3. Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM (2018) Lessons in PROTAC design from selective degradation with a promiscuous warhead. Cell Chem Biol 25:78–87
4. Burslem GM, Smith BE, La AC, Crew AP, Hines J, Crews CM, Jaime-Figueroa S et al (2018) The advantages of targeted protein degradation over inhibition: an RTK case study. Cell Chem Biol 25(1):67–77
5. Cecchini C, Tardy S, Scapozza L (2022) Linkers as game-changers in PROTAC technology: emphasizing general trends in PROTAC pharmacokinetics for their rational design. Chimia 76:341–345
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