Development and effect of antibodies to anakinra during treatment of severe CAPS: sub-analysis of a long-term safety and efficacy study
Author:
Funder
Swedish Orphan Biovitrum AB
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Rheumatology
Link
http://link.springer.com/article/10.1007/s10067-018-4196-x/fulltext.html
Reference18 articles.
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2. Martinon F, Tschopp J (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561–574. https://doi.org/10.1016/j.cell.2004.05.004
3. Hawkins PN, Lachmann HJ, McDermott MF (2003) Interleukin-1 receptor antagonist in the muckle-wells syndrome. N Engl J Med 348:2583–2584. https://doi.org/10.1056/NEJM200306193482523
4. Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, Anderson JP, Wanderer AA, Firestein GS (2004) Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 364:1779–1785. https://doi.org/10.1016/S0140-6736(04)17401-1
5. Lachmann HJ, Lowe P, Felix SD, Rordorf C, Leslie K, Madhoo S, Wittkowski H, Bek S, Hartmann N, Bosset S, Hawkins PN, Jung T (2009) In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes. J Exp Med 206(5):1029–1036. https://doi.org/10.1084/jem.20082481
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