Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics
Author:
Publisher
Springer International Publishing
Link
http://link.springer.com/content/pdf/10.1007/7515_2020_2
Reference92 articles.
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2. Anckar J, Sistonen L (2011) Regulation of HSF1 function in the heat stress response: implications in aging and disease. Annu Rev Biochem 80:1089–1115
3. Arora N, Alsaied O, Dauer P, Majumder K, Modi S, Giri B, Dudeja V, Banerjee S, Von Hoff D, Saluja A (2017) Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer. PLoS One 12(2):e0171827
4. Bach M, Lehmann A, Brünnert D, Vanselow JT, Hartung A, Bargou RC, Holzgrabe U, Schlosser A, Chatterjee M (2017) Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells. J Med Chem 60(10):4147–4160. https://doi.org/10.1021/acs.jmedchem.6b01613
5. Banerjee S, Saluja A (2015) Minnelide, a novel drug for pancreatic and liver cancer. Pancreatology 15(4 Suppl):S39–S43
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