Co-occurring genetic alterations predict distant metastasis and poor efficacy of first-line EGFR-TKIs in EGFR-mutant NSCLC-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Co-occurring genetic alterations predict distant metastasis and poor efficacy of first-line EGFR-TKIs in EGFR-mutant NSCLC

Published:2019-08-28 Issue:10 Volume:145 Page:2613-2624
ISSN:0171-5216
Container-title:Journal of Cancer Research and Clinical Oncology
language:en
Short-container-title:J Cancer Res Clin Oncol

Author:

Deng Li-Li,Gao Ge,Deng Hong-Bin,Wang Feng,Wang Zhi-Hui,Yang Yu^ORCID

Funder

Postdoctoral Scientific Research Developmental Fund provided by the Administration Office of Heilongjiang Postdoctoral Program

Wu Jieping medical foundation

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00432-019-03001-2.pdf

Reference35 articles.

1. Blakely CM, Watkins TBK, Wu W, Gini B, Chabon JJ, McCoach CE et al (2017) Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nat Genet 49(12):1693–1704. https://doi.org/10.1038/ng.3990

2. Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30(15):2114–2120. https://doi.org/10.1093/bioinformatics/btu170

3. Breindel JL, Haskins JW, Cowell EP, Zhao M, Nguyen DX, Stern DF (2013) EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Can Res 73(16):5053–5065. https://doi.org/10.1158/0008-5472.Can-12-3775

4. Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A et al (2015) PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion. Proc Natl Acad Sci USA. 112(28):8638–8643. https://doi.org/10.1073/pnas.1500722112

5. Canale M, Petracci E, Delmonte A, Chiadini E, Dazzi C, Papi M et al (2017) Impact of TP53 mutations on outcome in EGFR-mutated patients treated with first-line tyrosine kinase inhibitors. Clin Cancer Res 23(9):2195–2202. https://doi.org/10.1158/1078-0432.CCR-16-0966

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. EGFR and K-Ras Gene Mutations in the Diagnosis of Non-Small Cell Lung Cancer and their Pathological Correlation;International Journal of Pharmacology;2024-06-15

2. Coexpression of TP53, BIM, and PTEN Enhances the Therapeutic Efficacy of Non-Small-Cell Lung Cancer;Biomacromolecules;2024-01-18

3. Genetic alterations predict poor efficacy, outcomes and resistance to second-line osimertinib treatment in non-small cell lung cancer;American Journal of Cancer Research;2024

4. The impact of genomic context on outcomes of solid cancer patients treated with genotype-matched targeted therapies: a comprehensive review;Annals of Oncology;2023-12

5. NF1 alterations in cancers: therapeutic implications in precision medicine;Expert Opinion on Investigational Drugs;2023-10-03

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3