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CMTM6, a potential immunotherapy target

  • Published:2021-11-16 Issue:1 Volume:148 Page:47-56
  • ISSN:0171-5216
  • Container-title:Journal of Cancer Research and Clinical Oncology
  • language:en
  • Short-container-title:J Cancer Res Clin Oncol

Author:

Liang Jie,Li Shaohua,Li Wei,Rao Wei,Xu Shuo,Meng Haining,Zhu Fengqi,Zhai Dongchang,Cui Mengli,Xu Dan,Cai Jinzhen,Zhang Bei

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference60 articles.

1. Burr ML, Sparbier CE, Chan YC, Williamson JC, Woods K, Beavis PA, Lam EYN, Henderson MA, Bell CC, Stolzenburg S, Gilan O, Bloor S, Noori T, Morgens DW, Bassik MC, Neeson PJ, Behren A, Darcy PK, Dawson SJ, Voskoboinik I, Trapani JA, Cebon J, Lehner PJ, Dawson MA (2017) CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature 549:101–105. https://doi.org/10.1038/nature23643

2. Burugu S, Dancsok AR, Nielsen TO (2018) Emerging targets in cancer immunotherapy. Semin Cancer Biol 52:39–52. https://doi.org/10.1016/j.semcancer.2017.10.001

3. Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W (2018) Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Nature 560:382–386. https://doi.org/10.1038/s41586-018-0392-8

4. Chen L, Yang QC, Li YC, Yang LL, Liu JF, Li H, Xiao Y, Bu LL, Zhang WF, Sun ZJ (2020) Targeting CMTM6 suppresses stem cell-like properties and enhances antitumor immunity in head and neck squamous cell carcinoma. Cancer Immunol Res 8:179–191. https://doi.org/10.1158/2326-6066.cir-19-0394

5. Choi J, Jo C, Lim YS (2021) Tenofovir versus entecavir on recurrence of hepatitis B virus-related hepatocellular carcinoma after surgical resection. Hepatology 73:661–673. https://doi.org/10.1002/hep.31289
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