The dark genome and pleiotropy: challenges for precision medicine
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://link.springer.com/content/pdf/10.1007/s00335-019-09813-4.pdf
Reference25 articles.
1. Bowl MR, Simon MM, Ingham NJ et al (2017) A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat Commun 8:886. https://doi.org/10.1038/s41467-017-00595-4
2. Boyle EA, Li YI, Pritchard JK (2017) An expanded view of complex traits: from polygenic to omnigenic. Cell 169:1177–1186. https://doi.org/10.1016/j.cell.2017.05.038
3. Brown SDM, Moore MW (2012) The international mouse phenotyping consortium: past and future perspectives on mouse phenotyping. Mamm Genome 23:632–640. https://doi.org/10.1007/s00335-012-9427-x
4. Chesmore K, Bartlett J, Williams SM (2018) The ubiquity of pleiotropy in human disease. Hum Genet 137:39–44. https://doi.org/10.1007/s00439-017-1854-z
5. Collins FS, Varmus H (2015) A new initiative on precision medicine. N Engl J Med 372:793–795. https://doi.org/10.1056/NEJMp1500523
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