The ubiquity of pleiotropy in human disease-Reference-Cited by-同舟云学术

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The ubiquity of pleiotropy in human disease

Published:2017-11-21 Issue:1 Volume:137 Page:39-44
ISSN:0340-6717
Container-title:Human Genetics
language:en
Short-container-title:Hum Genet

Author:

Chesmore Kevin,Bartlett Jacquelaine,Williams Scott M.^ORCID

Funder

U.S. National Library of Medicine

National Institute of General Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics

Link

http://link.springer.com/article/10.1007/s00439-017-1854-z/fulltext.html

Reference22 articles.

1. Albert AY et al (2008) The genetics of adaptive shape shift in stickleback: pleiotropy and effect size. Evolution 62:76–85. https://doi.org/10.1111/j.1558-5646.2007.00259.x

2. Bulik-Sullivan B et al (2015) An atlas of genetic correlations across human diseases and traits. Nat Genet 47:1236–1241. https://doi.org/10.1038/ng.3406

3. Chung D, Yang C, Li C, Gelernter J, Zhao H (2014) GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS Genet 10:e1004787. https://doi.org/10.1371/journal.pgen.1004787

4. Hill WG, Zhang XS (2012) On the pleiotropic structure of the genotype-phenotype map and the evolvability of complex organisms. Genetics 190:1131–1137. https://doi.org/10.1534/genetics.111.135681

5. Ittisoponpisan S, Alhuzimi E, Sternberg MJ, David A (2017) Landscape of pleiotropic proteins causing human disease: structural and system biology insights. Hum Mutat 38:289–296. https://doi.org/10.1002/humu.23155

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