The DNA Methyltransferase Inhibitor RG108 is Converted to Activator Following Conjugation with Short Peptides-Reference-Cited by-同舟云学术

The DNA Methyltransferase Inhibitor RG108 is Converted to Activator Following Conjugation with Short Peptides

Published:2022-03-21 Issue:3 Volume:28 Page:
ISSN:1573-3904
Container-title:International Journal of Peptide Research and Therapeutics
language:en
Short-container-title:Int J Pept Res Ther

Author:

Rodríguez-Mejía Leslie C.,Romero-Estudillo Ivan,Rivillas-Acevedo Lina A.,French-Pacheco Leidys,Silva-Martínez Guillermo A.,Alvarado-Caudillo Yolanda,Colín-Castelán Dannia,Rodríguez-Ríos Dalia,Wrobel Katarzyna,Wrobel Kazimierz,Lund Gertrud,Zaina Silvio^ORCID

Funder

CONACyT

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Link

https://link.springer.com/content/pdf/10.1007/s10989-022-10390-5.pdf

Reference64 articles.

1. Asgatay S, Champion C, Marloie G et al (2014) Synthesis and evaluation of analogues of N-phthaloyl- l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1. J Med Chem 57:421–434. https://doi.org/10.1021/jm401419p

2. Assis RIF, Wiench M, Silvério KG et al (2018) RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation. PLoS ONE 13:e0207873. https://doi.org/10.1371/journal.pone.0207873

3. Assis RIF, Schmidt AG, Racca F et al (2021) DNMT1 inhibitor restores RUNX2 expression and mineralization in periodontal ligament cells. DNA Cell Biol 40:662–674. https://doi.org/10.1089/dna.2020.6239

4. Behrendt R, White P, Offer J (2016) Advances in Fmoc solid-phase peptide synthesis. J Pept Sci 22:4–27. https://doi.org/10.1002/psc.2836

5. Berillo D, Yeskendir A, Zharkinbekov Z et al (2021) Peptide-based drug delivery systems. Medicina (kaunas). https://doi.org/10.3390/medicina57111209

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