RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation

Author:

Assis Rahyza I. F.,Wiench Malgorzata,Silvério Karina G.,da Silva Rodrigo A.,Feltran Geórgia da Silva,Sallum Enilson A.,Casati Marcio Z.,Nociti Francisco H.,Andia Denise C.ORCID

Funder

São Paulo Research Foundation - FAPESP

Marie Curie Actions Career Integration Grant

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference36 articles.

1. Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells;SJ Greco;Stem Cells,2007

2. Transcriptional regulation of Oct4 in human bone marrow mesenchymal stem cells;X Wei;Stem Cells Dev,2011

3. Core transcriptional regulatory circuitry in human embryonic stem cells;LA Boyer;Cell,2005

4. Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells;CC Tsai;Mol Cell,2012

5. NANOG-dependent function of TET1 and TET2 in establishment of pluripotency;Y Costa;Nature,2013

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