Synergistic Therapy of Doxorubicin with Cationic Anticancer Peptide L-K6 Reverses Multidrug Resistance in MCF-7/ADR Cancer Cells In Vitro via P-glycoprotein Inhibition-Reference-Cited by-同舟云学术

Synergistic Therapy of Doxorubicin with Cationic Anticancer Peptide L-K6 Reverses Multidrug Resistance in MCF-7/ADR Cancer Cells In Vitro via P-glycoprotein Inhibition

Published:2021-07-10 Issue:4 Volume:27 Page:2291-2301
ISSN:1573-3149
Container-title:International Journal of Peptide Research and Therapeutics
language:en
Short-container-title:Int J Pept Res Ther

Author:

Wang Che,Huang Lili,Li Ruojin,Wang Ying,Wu Xiaoxue,Shang Dejing

Funder

National Natural Science Foundation of China

Scientific Research Fund of Liaoning Provincial Education Department

the Program for Liaoning Innovative Research Team in University

Natural Science Foundation of Liaoning Department of Science and Technology

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Link

https://link.springer.com/content/pdf/10.1007/s10989-021-10253-5.pdf

Reference33 articles.

1. Ambo A, Ohkatsu H, Minamizawa M, Watanabe H, Sugawara S, Nitta K, Tsuda Y, Okada Y, Sasaki Y (2012) Relationship between structure and P-glycoprotein inhibitory activity of dimeric peptides related to the Dmt-Tic pharmacophore. Bioorg Med Chem Lett 22:2192–2194. https://doi.org/10.1016/j.bmcl.2012.01.107

2. Ambudkar SV, Kimchi-sarfaty C, Sauna ZE, Gottesman MM (2003) P-glycoprotein: from genomics to mechanism. Oncogene 22:7468–7485. https://doi.org/10.1038/sj.onc.1206948

3. Anuchapreeda S, Leechanachai P, Smith MM, Ambudkar SV, Limtrakul PN (2002) Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem Pharmacol 64:573–582. https://doi.org/10.1016/s0006-2952(02)01224-8

4. Banković J, Andrä J, Todorović N, Podolski-Renić A, Milošević Z, Miljković D, Krause J, Ruždijić S, Tanić N, Pešić M (2013) The elimination of P-glycoprotein over-expressing cancer cells by antimicrobial cationic peptide NK-2: the unique way of multi-drug resistance modulation. Exp Cell Res 319:1013–1027. https://doi.org/10.1016/j.yexcr.2012.12.017

5. Dönmez Y, Akhmetova L, İşeri ÖD, Kars MD, Gündüz U (2011) Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells. Cancer Chemother Pharmacol 67:823–828. https://doi.org/10.1007/s00280-010-1385-y

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cationic anticancer peptide L-K6-modified and doxorubicin-loaded mesoporous silica nanoparticles reverse multidrug resistance of breast cancer;Arabian Journal of Chemistry;2024-05

2. Recent advances and applications of peptide–agent conjugates for targeting tumor cells;Journal of Cancer Research and Clinical Oncology;2023-08-15

3. Temporins: Multifunctional Peptides from Frog Skin;International Journal of Molecular Sciences;2023-03-12

4. Phytochemical profiling, molecular docking, and anti-hepatocellular carcinoid bioactivity of extracts;Arabian Journal of Chemistry;2022-07

5. Characterization and Anticancer Activity of a Folic Acid Conjugated and Cationic Peptide L-K6 Encapsulated Cancer-Targeting Liposomal Drug Delivery System;International Journal of Peptide Research and Therapeutics;2022-03-26