Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells-Reference-Cited by-同舟云学术

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Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells

Published:2010-06-19 Issue:4 Volume:67 Page:823-828
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Dönmez Yaprak,Akhmetova Laila,İşeri Özlem Darcansoy,Kars Meltem Demirel,Gündüz Ufuk

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s00280-010-1385-y.pdf

Reference29 articles.

1. Ambudkar S, Kimchi-Sarfaty C, Sauna Z, Gottesman M (2003) P-glycoprotein: from genomics to mechanism. Oncogene 22:7468–7485

2. Anuchapreeda S, Leechanachai P, Smith MM, Ambudkar SV, Limtrakul PN (2002) Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem Pharmacol 64:573–582

3. Callaghan R, Stafford A, Epand RM (1993) Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties. Biochim Biophys Acta 1175:277–282

4. Dalton WS (1997) Mechanisms of drug resistance in hematologic malignancies. Semin Hematol 34:3–8

5. Drori S, Eytan GD, Assaraf YG (1995) Potentiation of anticancer drug cytotoxicity by multidrug resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability. Eur J Biochem 228:1020–1029

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