HESA-A Attenuates Hepatic Steatosis in NAFLD Rat Model Through the Suppression of SREBP-1c and NF-kβ

Author:

Efati M.,Khorrami M.,Jangravi Z.,Mahmoudabadi A. Z.,Raeiszadeh M.,Sarshoori J. R.

Funder

Baqiyatallah University of Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry

Reference49 articles.

1. Abbasi MM, Mehdipour M, Monfaredan A, Jahanban-Esfahlan R (2015) Hesa-A down-regulates erb/b2 oncogene expression and improves outcome of oral carcinoma in a rat model. Asian Pac J Cancer Prev 16(16):6947–6951

2. Ahmadi A (2006) Cytotoxicity and antitumor properties of a marine compound on cancer cells, HESA-A. Cancer Epidemiol Biomark Prevent 15(12 Supplement):B91

3. Ahmadi A, Mohagheghi MA, Fazeli MS, Nahavandian B, Bashardoost N, Jarahi AM, et al (2005) HESA-A: new treatment for breast cancer and choroidal metastasis. Med Sci Monit 11(6):CR300–3

4. Ahmadi A, Naderi G, Asgary S (2005) Evaluation of hepatoprotective potential of HESA-A (a marine compound) pretreatment against thioacetamide-induced hepatic damage in rabbits. Drugs Exp Clin Res 31(1):1–6

5. Ahmadi A, Mohagheghi M, Karimi M, Seyed Ali G, Naseri M (2009) Anticancer effects of HESA-A in patients with metastatic colon cancer. Integr Cancer Ther 8(1):71–74

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