Analysis of the cytotoxic effects of ruthenium–ketoconazole and ruthenium–clotrimazole complexes on cancer cells

Author:

Robles-Escajeda Elisa,Martínez Alberto,Varela-Ramirez Armando,Sánchez-Delgado Roberto A.,Aguilera Renato J.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Cell Biology,Toxicology

Reference73 articles.

1. Aird RE, Cummings J, Ritchie AA, Muir M, Morris RE, Chen H, et al. In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer. Br J Cancer. 2002;86(10):1652–7.

2. Anzelloti A. Study of possible mechanisms of action of ruthenium–azole complexes against Trypanosoma cruzi. Venezuelan Institute for Scientific Research (IVIC), Caracas, Venezuela; M.Sc. Thesis. 2004.

3. Bergamo A, Gagliardi R, Scarcia V, Furlani A, Alessio E, Mestroni G, et al. In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin. J Pharmacol Exp Ther. 1999;289(1):559–64.

4. Berger MR, Garzon FT, Keppler BK, Schmahl D. Efficacy of new ruthenium complexes against chemically induced autochthonous colorectal carcinoma in rats. Anticancer Res. 1989;9(3):761–5.

5. Bok RA, Small EJ. The treatment of advanced prostate cancer with ketoconazole: safety issues. Drug Saf. 1999;20(5):451–8.

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