Non-obstructive Plaque and Treatment of INOCA: More to Be Learned

Author:

Ya’Qoub LinaORCID,Elgendy Islam Y.ORCID,Pepine Carl J.ORCID

Funder

National Institutes of Health

U.S. Department of Defense

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference30 articles.

1. Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2022 Update: a report from the American Heart Association. Circulation 2022;145(8):e153–e639. https://doi.org/10.1161/CIR.0000000000001052.

2. Elgendy IY, Ya’Qoub L, Chen KH, Pepine CJ. Coronary microvascular dysfunction in patients with non-obstructive coronary arteries: current gaps and future directions. Drugs 2022;82(3):241–250. https://doi.org/10.1007/s40265-021-01667-y.

3. Ya’qoub L, Elgendy IY, Pepine CJ. Syndrome of nonobstructive coronary artery diseases: a comprehensive overview of open artery ischemia. Am J Med. 2021;134(11):1321–9. https://doi.org/10.1016/j.amjmed.2021.06.038.

4. Bairey Merz CN, Pepine CJ, Walsh MN, Fleg JL. Ischemia and No Obstructive Coronary Artery Disease (INOCA): developing evidence-based therapies and research agenda for the next decade. Circulation. 2017;135:1075–92. https://doi.org/10.1161/CIRCULATIONAHA.116.024534.

5. Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, et al. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation endorsed by Coronary Vasomotor Disorders International Study Group. EuroIntervention 2021;16:1049–69. https://doi.org/10.4244/EIJY20M07_01. This reference represents an expert consensus document for diagnosis and current management of patients with INOCA; it is important because it provides comprehensive data regarding the diagnosis and management approaches for INOCA based on the scientific evidence at the present time.

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