A Randomized Controlled Trial on the Efficacy and Safety of Low-Dose hCG in a Short Protocol with GnRH Agonist and Ovarian Stimulation with Recombinant FSH (rFSH) During the Follicular Phase in Infertile Women Undergoing ART

Author:

Siristatidis CharalamposORCID,Stavros SofoklisORCID,Dafopoulos KonstantinosORCID,Sergentanis TheodorosORCID,Domali EkateriniORCID,Drakakis PeterORCID,Loutradis DimitriosORCID

Publisher

Springer Science and Business Media LLC

Subject

Obstetrics and Gynecology

Reference45 articles.

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2. Balasch J, Creus M, Fábregues F, Civico S, Carmona F, Puerto B, et al. The effect of exogenous luteinizing hormone [LH] on oocyte viability: evidence from a comparative study using recombinant human follicle-stimulating hormone [FSH] alone or in combination with recombinant LH for ovarian stimulation in pituitary-suppressed women undergoing assisted reproduction. J Assist Reprod Genet. 2001;18(5):250–6. https://doi.org/10.1023/a:1016662100572.

3. Casarini L, Lispi M, Longobardi S, Milosa F, La Marca A, Tagliasacchi D, et al. LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling. PLoS One. 2012;7(10):e46682. https://doi.org/10.1371/journal.pone.0046682.

4. Casarini L, Riccetti L, De Pascali F, Nicoli A, Tagliavini S, Trenti T, et al. Follicle-stimulating hormone potentiates the steroidogenic activity of chorionic gonadotropin and the anti-apoptotic activity of luteinizing hormone in human granulosa-lutein cells in vitro. Mol Cell Endocrinol. 2016;422:103–14. https://doi.org/10.1016/j.mce.2015.12.008.

5. Chandrasekher YA, Hutchison JS, Zelinski-Wooten MB, Hess DL, Wolf DP, Stouffer RL. Initiation of periovulatory events in primate follicles using recombinant and native human luteinizing hormone to mimic the midcycle gonadotropin surge. J Clin Endocrinol Metab. 1994;79(1):298–306. https://doi.org/10.1210/jcem.79.1.8027245.

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