Effect of Berberine on Activation of TLR4-NFκB Signaling Pathway and NLRP3 Inflammasome in Patients with Gout

Author:

Dang Wan-tai,Xu Dan,Zhou Jing-guo

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Complementary and alternative medicine,General Medicine

Reference39 articles.

1. Richette P, Bardin T. Gout. Lancet 2010;375:318–328.

2. van Durme CM, Spaetgens B, Boonen A, de Vries F. Risk of vascular disease with gout: overadjustment of the statistical analyses? Ann Rheum Dis 2015;74:e9.

3. Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med 2015;21:248–255.

4. Zhang Y, Lu Y, Ma L, Cao X, Xiao J, Chen J, et al. Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NFκB signaling and protects against endotoxin shock. Immunity 2014;40:501–514.

5. Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, et al. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell 2015;160:62–73.

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