Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice

Author:

Zhang Yueyi,Wang Shan,Dai Xuan,Liu Tianyuan,Liu Yage,Shi Hanfen,Yin Jiyuan,Xu Tianshu,Zhang Yanfei,Zhao Dandan,Sukhorukov Vasily,Orekhov Alexander N.,Gao Sihua,Wang Lili,Zhang DongweiORCID

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference68 articles.

1. Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: a uric acid modulator targeting Keap1-Nrf2/NLRP3 axis;Ai;J. Ethnopharmacol.,2023

2. A flavonoid-rich fraction of Monolluma quadrangula inhibits xanthine oxidase and ameliorates potassium oxonate-induced hyperuricemia in rats;Alrashdi;Environ. Sci. Pollut. Res. Int.,2022

3. Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis;Bao;Phytomedicine,2022

4. The anti-inflammatory and uric acid lowering effects of Si-Miao-San on gout;Cao;Front. Immunol.,2021

5. Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats;Chen;J. Ethnopharmacol.,2021

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