Discovery of novel BRD4-BD2 inhibitors via in silico approaches: QSAR techniques, molecular docking, and molecular dynamics simulations-Reference-Cited by-同舟云学术

Discovery of novel BRD4-BD2 inhibitors via in silico approaches: QSAR techniques, molecular docking, and molecular dynamics simulations

Published:2023-02-11 Issue: Volume: Page:
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Tong Jian-Bo,Xiao Xue-Chun,Luo Ding,Xu Hai-Yin,Xing Yi-Chuang,Gao Peng,Liu Yuan

Funder

National Natural Science Funds of China

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s11030-023-10611-z.pdf

Reference39 articles.

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2. Yang H, Li W, Xun Y, Yang AP, You H (2021) BRD4: An emerging prospective therapeutic target in glioma. Mol Ther Oncolytics 21:1–14. https://doi.org/10.1016/j.omto.2021.03.005

3. Donati B, Lorenzini E, Ciarrocchi A (2018) BRD4 and Cancer: going beyond transcriptional regulation. Mol Cancer 17:1–13. https://doi.org/10.1186/s12943-018-0915-9

4. Lu T, Lu WC, Luo C (2020) A patent review of BRD4 inhibitors (2013–2019). Expert Opin Ther Patents 30:57–81. https://doi.org/10.1080/13543776.2020.1702645

5. Duan YC, Guan YY, Qin WP, Zhai XY, Yu B, Liu HM (2018) Targeting Brd4 for cancer therapy: inhibitors and degraders. Medchemcomm 9:1779–1802. https://doi.org/10.1039/c8md00198g

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