Three-dimensional quantitative structural-activity relationship and molecular dynamics study of multivariate substituted 4-oxyquinazoline HDAC6 inhibitors-Reference-Cited by-同舟云学术

Three-dimensional quantitative structural-activity relationship and molecular dynamics study of multivariate substituted 4-oxyquinazoline HDAC6 inhibitors

Published:2022-06-29 Issue: Volume: Page:
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Zhao Linan,Fu Le,Li Guangping,Yu Yongxin,Wang Juan,Liang Haoran,Shu Mao,Lin Zhihua,Wang Yuanqiang

Funder

Support Program for Starting up Innovation Hub

State Key Laboratory of Silkworm Genome Biology Funded by State Key Laboratory of Silkworm Genome Biology, Science and Technology Bureau of Banan District, Chongqing

Scientific Research Foundation of Graduate School of Harbin Medical University: Sino Russian Special Fund

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s11030-022-10474-w.pdf

Reference72 articles.

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3. Heckman CA, Duan H, Boxer LM (2013) Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas. Mol Cell Biol 25(5):1608–1619. https://doi.org/10.1128/MCB.25.5.1608-1619.2005

4. Luo JY, Su F, Chen D et al (2000) Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature 408:377–381. https://doi.org/10.1038/35042612

5. Minucci S, Nervi C, Coco FL et al (2001) Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias? Oncogene 20:3110. https://doi.org/10.1038/sj.onc.1204336

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