Discovery of Novel Imidazo[1,2-<i>a</i>]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect-Reference-Cited by-同舟云学术

Discovery of Novel Imidazo[1,2-a]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect

Published:2024-08-05 Issue:16 Volume:67 Page:14345-14369
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Fei-Fei¹²,Liu Jing-Jing¹,Xu Xue-Li¹,Hu Ting¹,Liu Jian-Quan¹,He Zhang-Xu²,Zhao Guang-Yuan¹,Wei Bo¹,Ma Li-Ying¹³^ORCID

Affiliation:

1. State Key Laboratory of Esophageal Cancer Prevention and Treatment; Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China; School of Pharmaceutical Science and Institute of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, China

2. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China

3. China Meheco Topfond Pharmaceutical Co.; Key Laboratory of Cardio-cerebrovascular Drug, Zhumadian 463000, China

Funder

Natural Science Foundation of Henan Province

China Postdoctoral Science Foundation

Science and Technology Innovation Talents in Universities of Henan Province

National Natural Science Foundation of China

Joint Fund for Science and Technology Research and Development Plan of Henan province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01168

Reference62 articles.

1. The contributory roles of histone deacetylases (HDACs) in hematopoiesis regulation and possibilities for pharmacologic interventions in hematologic malignancies

2. The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies

3. Inhibition of HDAC6 Activity Alleviates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Potential Role of Peroxiredoxin 1 Acetylation and Redox Regulation

4. Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion

5. Preparation of injectable clopidogrel loaded submicron emulsion for enhancing physicochemical stability and anti-thrombotic efficacy