A facile, regioselective synthesis of novel 3-(N-phenylcarboxamide)pyrazolo[1,5-a]pyrimidine analogs in the presence of KHSO $$_{4}$$ 4 in aqueous media assisted by ultrasound and their antibacterial activities-Reference-Cited by-同舟云学术

A facile, regioselective synthesis of novel 3-(N-phenylcarboxamide)pyrazolo[1,5-a]pyrimidine analogs in the presence of KHSO $$_{4}$$ 4 in aqueous media assisted by ultrasound and their antibacterial activities

Published:2015-10-28 Issue:2 Volume:20 Page:379-390
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Kaping Shunan,Boiss Ivee,Singha Laishram Indira,Helissey Philippe,Vishwakarma Jai N.

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

http://link.springer.com/content/pdf/10.1007/s11030-015-9639-6.pdf

Reference49 articles.

1. Zask A, Verheijen JC, Curran K, Kaplan J, Richard DJ, Nowak P, Malwitz DJ, Brooijmans N, Bard J, Svenson K, Lucas J, Toral-Barza L, Zhang WG, Hollander I, Gibbons JJ, Abraham RT, Ayral-Kaloustian S, Mansour TS, Yu K (2009) ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines. J Med Chem 52:5013–5016. doi: 10.1021/jm900851f

2. Curran K, Verheijen JC, Kaplan J, Richard DJ, Toral-Barza L, Hollander I, Lucas J, Ayral-Kaloustian S, Yu K, Zask A (2010) Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 1-substituent. Bioorg Med Chem Lett 20:1440–1444. doi: 10.1016/j.bmcl.2009.12.086

3. Stefano A, Anna A, Maurizio B, Alessandra T, Francisco O, Francesco O, Silvia S, Chiara B, Matilde Y (2010) Hit identification and biological evaluation of anticancer pyrazolopyrimidines endowed with anti-inflammatory activity. Chem Med Chem 5:1242–1246. doi: 10.1002/cmdc.201000165

4. Huang S, Lin R, Yu Y, Lu Y, Conolly P, Chiu G, Li S, Emanuel S, Middleton S (2007) Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor. Bioorg Med Chem Lett 17:1243–1245. doi: 10.1016/j.bmcl.2006.12.031

5. Mukaiyama H, Nishimura T, Kobayashi S, Komatsu Y (2008) Novel pyrazolo[1,5- $$a$$ a ]pyrimidines as c-Src kinase inhibitors that reduce $$I_{{\rm Kr}}$$ I Kr channel blockade. Bioorg Med Chem 16:909–921. doi: 10.1016/j.bmc.2007.10.068

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