Characteristic structural difference between inactive and active states of orexin 2 receptor determined using molecular dynamics simulations
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology,Biophysics
Link
https://link.springer.com/content/pdf/10.1007/s12551-021-00862-1.pdf
Reference69 articles.
1. Chan HCS, Li Y, Dahoun T, Vogel H, Yuan SG (2019) New binding sites, new opportunities for gpcr drug discovery. Trends Biochem Sci 44(4):312–330. https://doi.org/10.1016/j.tibs.2018.11.011
2. Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL (2018) Structure of the nanobody-stabilized active state of the kappa opioid receptor. Cell 172 (1-2):55–67. https://doi.org/10.1016/j.cell.2017.12.011
3. Che T, English J, Krumm BE, Kim K, Pardon E, Olsen RHJ, Wang S, Zhang S, Diberto JF, Sciaky N, Carroll FI, Steyaert J, Wacker D, Roth BL (2020) Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun 11(1). https://doi.org/10.1038/s41467-020-14889-7
4. Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Mueller CE, Stevens RC (2019) Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists. Sci Adv 5(11). https://doi.org/10.1126/sciadv.aax9115
5. Dickson CJ, Madej BD, Skjevik AA, Betz RM, Teigen K, Gould IR, Walker RC (2014) Lipid14: The amber lipid force field. J Chem Theory Comput 10:865–879. https://doi.org/10.1021/ct4010307
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