Das Two-in-one-hit-Modell der beschleunigten Genese von kolorektalen Karzinomen beim MLH1-assoziierten Lynch-Syndrom
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pathology and Forensic Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00292-023-01245-x.pdf
Reference11 articles.
1. Ahadova A, Stenzinger A, Seppälä T, Hüneburg R, Kloor M, Bläker H (2023) A “two-in-one hit” model of shortcut carcinogenesis in MLH1 lynch syndrome carriers. Gastroenterology 165(1):267–270.e4. https://doi.org/10.1053/j.gastro.2023.03.007
2. Arnold A, Tronser M, Sers C, Ahadova A, Endris V, Mamlouk S, Horst D, Möbs M, Bischoff P, Kloor M, Bläker H (2020) Correction to: The majority of β‑catenin mutations in colorectal cancer is homozygous. Bmc Cancer 20(1):1151. https://doi.org/10.1186/s12885-020-07645-z
3. Berger AW, Raedler K, Langner C, Ludwig L, Dikopoulos N, Becker KF, Slotta-Huspenina J, Quante M, Schwerdel D, Perkhofer L, Kleger A, Zizer E, Oswald F, Seufferlein T, Meining A (2018) Genetic biopsy for prediction of surveillance intervals after endoscopic resection of colonic polyps: results of the GENESIS study. United European Gastroenterol J 6(2):290–299. https://doi.org/10.1177/2050640617723810
4. ten Broeke SW, van Bavel TC, Jansen AML, Gómez-García E, Hes FJ, van Hest LP, Letteboer TGW, Olderode-Berends MJW, Ruano D, Spruijt L, Suerink M, Tops CM, van Eijk R, Morreau H, van Wezel T, Nielsen M (2018) Molecular background of colorectal tumors from patients with lynch syndrome associated with Germline variants in PMS2. Gastroenterology 155(3):844–851. https://doi.org/10.1053/j.gastro.2018.05.020
5. Engel C, Ahadova A, Seppälä TT et al (2020) Associations of pathogenic variants in MLH1, MSH2, and MSH6 with risk of colorectal Adenomas and tumors and with somatic mutations in patients with lynch syndrome. Gastroenterology 158(5):1326–1333. https://doi.org/10.1053/j.gastro.2019.12.032
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