Identification of serum biomarkers associated with hepatitis B virus-related hepatocellular carcinoma and liver cirrhosis using mass-spectrometry-based metabolomics

Author:

Lu Yonghai,Huang Chong,Gao Liang,Xu Yong-Jiang,Chia Sin Eng,Chen Shengsen,Li Ning,Yu Kangkang,Ling Qingxia,Cheng Qi,Zhu Mengqi,Chen Mingquan,Ong Choon Nam

Funder

Natural Science Fund of The Science and Technology Commission of Shanghai, China

Singapore Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Clinical Biochemistry,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference46 articles.

1. Baniasadi, H., Gowda, G. A., Gu, H., et al. (2013). Targeted metabolic profiling of hepatocellular carcinoma and hepatitis C using LC-MS/MS. Electrophoresis, 34, 2910–2917.

2. Beyoglu, D., Imbeaud, S., Maurhofer, O., et al. (2013). Tissue metabolomics of hepatocellular carcinoma: tumor energy metabolism and the role of transcriptomic classification. Hepatology, 58, 229–238.

3. Chaneton, B., Hillmann, P., Zheng, L., et al. (2012). Serine is a natural ligand and allosteric activator of pyruvate kinase M2. Nature, 491, 458–462.

4. Chen, T., Xie, G., Wang, X., et al. (2011). Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Molecular and Cellular Proteomics, 10(M110), 004945.

5. Chi, H. C., Chen, C. Y., Tsai, M. M., Tsai, C. Y., & Lin, K. H. (2013). Molecular functions of thyroid hormones and their clinical significance in liver-related diseases. Biomed Research International, 601361.

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