Topoisomerase i inhibition and cytotoxicity of licochalcones A and E fromGlycyrrhiza inflata
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF02977611.pdf
Reference20 articles.
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4. Constantinou, A., Mehta, R., Runyan, C, Rao, K., Vaughan, A., and Moon, R., Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.J. Nat. Prod., 58, 217–225 (1995).
5. Fu, Y, Hsieh, T. C, Guo, J., Kunicki, J., Lee, M. Y W. T., Darzynkiewicz, Z., and Wu, J. M., Licochalcone-A, a novel flavonoid isolated from licorice root(Glycyrrhiza glabra), causes G2 and Iate-G1 arrests in androgen-independent PC- 3 prostate cancer cells.Biochem. Biophys. Res. Commun., 322, 263–270 (2004).
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