Population Pharmacokinetic/Pharmacodynamic Modeling of O-Desmethyltramadol in Young and Elderly Healthy Volunteers
Author:
Funder
Labopharm Inc.
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Geriatrics and Gerontology
Link
http://link.springer.com/content/pdf/10.1007/s40266-019-00681-w.pdf
Reference49 articles.
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3. Chung J. Geriatric clinical pharmacology and clinical trials in the elderly. Transl Clin Pharmacol. 2014;22(2):64–9.
4. Chien JY, Ho RJ. Drug delivery trends in clinical trials and translational medicine: evaluation of pharmacokinetic properties in special populations. J Pharm Sci. 2011;100(1):53–8.
5. Lee CR, McTavish D, Sorkin EM. Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs. 1993;46(2):313–40.
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