Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients

Author:

Al-Qurain Aymen A.ORCID,Upton Richard N.,Tadros Rami,Roberts Michael S.,Wiese Michael D.

Funder

University of South Australia

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference42 articles.

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2. Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an’atypical’opioid analgesic. J Pharmacol Exp Ther. 1992;260(1):275–85.

3. Rahimi HR, Soltaninejad K, Shadnia S. Acute tramadol poisoning and its clinical and laboratory findings. J Res Med Sci. 2014;19(9):855.

4. Scott LJ, Perry CM. Tramadol: a review of its use in perioperative pain. Drugs. 2000;60(1):139–76.

5. Grond S, Meuser T, Uragg H, Stahlberg HJ, Lehmann KA. Serum concentrations of tramadol enantiomers during patient-controlled analgesia. Br J Clin Pharmacol. 1999;48(2):254–7.

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