Author:
Gas-Pascual Elisabet,Simonovik Biljana,Heintz Dimitri,Bergdoll Marc,Schaller Hubert,Bach Thomas J.
Subject
Cell Biology,Organic Chemistry,Biochemistry
Reference77 articles.
1. Cattel L, Ceruti M (1997) Inhibitors of 2,3-oxidosqualene cyclase as tools for studying the mechanism and function of the enzyme. In: Parish EJ, Nes WD (eds) Biochemistry and function of sterols. CRC Press, Boca-Raton, chapter 1, pp 1–21
2. Morand OH, Aebi JD, Dehmlow H, Ji Y-H, Gains N, Lengsfeld H, Himber J (1997) Ro 48-8071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin. J Lipid Res 38:273–390
3. Peffley DM, Gayzn AK, Morand OH (1998) Down-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels and synthesis in Syrian hamster C100 cells by the oxidosqualene cyclase inhibitor [4′-(6-allyl-ethyl-amino-hexyloxy)-2′-fluoro-phenyl]-(4-bromophenyl)-methanone (Ro 48-8071): comparison to simvastatin––comparison with inhibitors of HMG-CoA reductase. Biochem Pharmacol 56:439–449
4. Liang Y, Besch-Williford C, Aebi JD, Mafuvadze B, Cook MT, Zou X, Hyder SM (2014) Cholesterol biosynthesis inhibitors as potent novel anti-cancer agents: suppression of hormone-dependent breast cancer by the oxidosqualene cyclase inhibitor RO 48-8071. Breast Cancer Res Treat 146:51–62
5. Dang T, Abe I, Zheng Y-F, Prestwich GD (1999) The binding site for an inhibitor of squalene:hopene cyclase determined using photoaffinity labeling and molecular modeling. Chem Biol 6:333–341
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献