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Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice

  • Published:2015-10-01 Issue:1 Volume:29 Page:118-125
  • ISSN:1029-8428
  • Container-title:Neurotoxicity Research
  • language:en
  • Short-container-title:Neurotox Res

Author:

Aguiar Aderbal S.,Lopes Samantha C.,Tristão Fabrine S. M.,Rial Daniel,de Oliveira Gisele,da Cunha Cláudio,Raisman-Vozari Rita,Prediger Rui D.

Funder

CNPq

CAPES

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Reference48 articles.

1. Aguiar AS Jr, Speck AE, Prediger RD, Kapczinski F, Pinho RA (2008) Downhill training upregulates mice hippocampal and striatal brain-derived neurotrophic factor levels. J Neural Transm 115(9):1251–1255. doi: 10.1007/s00702-008-0071-2

2. Aguiar AS Jr, Castro AA, Moreira EL, Glaser V, Santos AR, Tasca CI, Latini A, Prediger RD (2011) Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and BDNF signaling. Mech Ageing Dev 132(11–12):560–567. doi: 10.1016/j.mad.2011.09.005

3. Aguiar AS Jr, Moreira EL, Hoeller AA, Oliveira PA, Cordova FM, Glaser V, Walz R, Cunha RA, Leal RB, Latini A, Prediger RD (2013a) Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice. Neuroscience 243:46–53. doi: 10.1016/j.neuroscience.2013.03.039

4. Aguiar AS Jr, Tristao FS, Amar M, Chevarin C, Lanfumey L, Mongeau R, Corti O, Prediger RD, Raisman-Vozari R (2013b) Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Neurotox Res 24(2):280–287. doi: 10.1007/s12640-013-9389-0

5. Aguiar AS Jr, Tristao FS, Amar M, Chevarin C, Glaser V, de Paula Martins R, Moreira EL, Mongeau R, Lanfumey L, Raisman-Vozari R, Latini A, Prediger RD (2014) Six weeks of voluntary exercise don’t protect C57BL/6 mice against neurotoxicity of MPTP and MPP(+). Neurotox Res 25(2):147–152. doi: 10.1007/s12640-013-9412-5

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