BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology-Reference-Cited by-同舟云学术

BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology

Published:2011-07-02 Issue:2 Volume:21 Page:160-174
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Cai Yan,Zhang Xue-Mei,Macklin Lauren N.,Cai Huaibin,Luo Xue-Gang,Oddo Salvatore,LaFerla Frank M.,Struble Robert G.,Rose Gregory M.,Patrylo Peter R.,Yan Xiao-Xin

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1007/s12640-011-9256-9.pdf

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3. Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19:939–945

4. Burgold S, Bittner T, Dorostkar MM, Kieser D, Fuhrmann M, Mitteregger G, Kretzschmar H, Schmidt B, Herms J (2011) In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks. Acta Neuropathol 121:327–335

5. Cai H, Wang Y, McCarthy D, Wen H, Borchelt DR, Price DL, Wong PC (2001) BACE1 is the major beta-secretase for generation of Aβ peptides by neurons. Nat Neurosci 4:233–234

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