Epigenetic therapy in combination with a multi-epitope cancer vaccine targeting shared tumor antigens for high-risk myelodysplastic syndrome - a phase I clinical trial
Author:
Funder
Kræftens Bekæmpelse
Herlev Hospital
Celgene
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Immunology,Immunology and Allergy
Link
https://link.springer.com/content/pdf/10.1007/s00262-021-02993-6.pdf
Reference50 articles.
1. Zeidan AM, Shallis RM, Wang R, Davidoff A, Ma X (2019) Epidemiology of myelodysplastic syndromes: why characterizing the beast is a prerequisite to taming it. Blood Rev 34:1–15
2. Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A et al (2009) Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 10:223–232
3. Bender CM, Pao MM, Jones PA (1998) Inhibition of DNA methylation by 5-Aza-2’-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res 58:95–101
4. Ørskov AD, Grønbæk K (2017) DNA methyltransferase Inhibitors in myeloid cancer: clonal eradication or clonal differentiation? Cancer J 23:277–285
5. Mund C, Hackanson B, Stresemann C, Lübbert M, Lyko F (2005) Characterization of DNA demethylation effects induced by 5-Aza-2′-deoxycytidine in patients with myelodysplastic syndrome. Cancer Res 65:7086–7090
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Oxidative stress-mediated epigenetic remodeling, metastatic progression and cell signaling in cancer;Oncologie;2024-07-01
2. Immunotherapies of acute myeloid leukemia: Rationale, clinical evidence and perspective;Biomedicine & Pharmacotherapy;2024-02
3. Wilms’ tumor 1 -targeting cancer vaccine: Recent advancements and future perspectives;Human Vaccines & Immunotherapeutics;2023-12-26
4. Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation;Molecular Cancer;2023-10-09
5. Co-Delivery of the Human NY-ESO-1 Tumor-Associated Antigen and Alpha-GalactosylCeramide by Filamentous Bacteriophages Strongly Enhances the Expansion of Tumor-Specific CD8+ T Cells;Viruses;2023-03-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3