Rapamycin Cannot Reduce Seizure Susceptibility in Infantile Rats with Malformations of Cortical Development Lacking mTORC1 Activation
Author:
Funder
Ministry of Education
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
https://link.springer.com/content/pdf/10.1007/s12035-022-03033-9.pdf
Reference47 articles.
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2. Crino PB (2019) Mechanistic target of rapamycin (mTOR) signaling in status epilepticus. Epilepsy Behav 101(Pt B):106550. https://doi.org/10.1016/j.yebeh.2019.106550
3. Crino PB (2016) The mTOR signalling cascade: paving new roads to cure neurological disease. Nat Rev Neurol 12(7):379–392. https://doi.org/10.1038/nrneurol.2016.81
4. Griffith JL, Wong M (2018) The mTOR pathway in treatment of epilepsy: a clinical update. Future Neurol 13(2):49–58. https://doi.org/10.2217/fnl-2018-0001
5. Weston MC, Chen H, Swann JW (2012) Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission. J Neurosci 32(33):11441–11452. https://doi.org/10.1523/JNEUROSCI.1283-12.2012
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