Expression of a Fragment of Ankyrin 2 Disrupts the Structure of the Axon Initial Segment and Causes Axonal Degeneration in Drosophila
Author:
Funder
National Institute of Neurological Disorders and Stroke
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
http://link.springer.com/content/pdf/10.1007/s12035-019-1477-6.pdf
Reference42 articles.
1. Rasband MN (2010) The axon initial segment and the maintenance of neuronal polarity. Nat Rev Neurosci 11(8):552–562. https://doi.org/10.1038/nrn2852
2. Palmer LM, Stuart GJ (2006) Site of action potential initiation in layer 5 pyramidal neurons. J Neurosci 26(6):1854–1863. https://doi.org/10.1523/JNEUROSCI.4812-05.2006
3. Evans MD, Dumitrescu AS, Kruijssen DLH, Taylor SE, Grubb MS (2015) Rapid modulation of axon initial segment length influences repetitive spike firing. Cell Rep 13(6):1233–1245. https://doi.org/10.1016/j.celrep.2015.09.066
4. Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008) Action potential generation requires a high sodium channel density in the axon initial segment. Nat Neurosci 11(2):178–186. https://doi.org/10.1038/nn2040
5. Khaliq ZM, Raman IM (2006) Relative contributions of axonal and somatic Na channels to action potential initiation in cerebellar Purkinje neurons. J Neurosci 26(7):1935–1944. https://doi.org/10.1523/JNEUROSCI.4664-05.2006
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