Author:
Veeck Christopher,Biedenkopf Nadine
Abstract
AbstractViruses employ cellular host factors not only for replication and transcription but also for transport and assembly. Rab-GTPases, as master regulators of intracellular trafficking pathways, are commonly involved host factors and useful tools for identification of transport pathways used but certain viruses. Here, we present Rab1B as an essential host factor for trafficking and maturation of the SARS-CoV-2 spike protein.
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology