Leflunomide, a novel immunomodulating drug, inhibits homotypic adhesion of peripheral blood and synovial fluid mononuclear cells in rheumatoid arthritis

Author:

Dimitrijevic M.,Bartlett R. R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Immunology

Reference40 articles.

1. Bartlett RR, Schleyerbach R. Immunopharmacological profile of a novel isoxazol derivate, HWA 486, with potential antirheumatic activity. I. Disease modifying action on adjuvant arthritis of the rat. Int J Immunopharm 1985;7:7–18.

2. Bartlett RR, Dimitrijevic M, Mattar T, Zielinski T, Germann T, Rude E, et al. Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of auto-immune disorders and reactions leading to transplantation rejection. Agents Actions 1991;32:10–21.

3. Ogawa T, Inazu M, Gotoh K, Hayashi S. Effects of leflunomide on glomerulonephritis induced by antibasement membrane antibody in rats. Agents Actions 1990;31:321–8.

4. Smith-Long L, Glaser B, Weimer LK, Miller ST, Robertson SM, Aoki KR, et al. Efficacy of novel immunomodulators leflunomide and rapamycin in autoimmune uveitis. FASEB J 1992;6:A1048.

5. Xiao F, Chong AS-F, Bartlett RR, Williams JW, Leflunomide: a promising immunosuppressant in transplantation. In: Thompson AW, Starzl TE, editors. Immunosuppressive Drugs. Developments in anti-rejection therapy. London: Edward Arnold, 1994;203–12.

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