Detection of in Vitro Metabolite Formation of Leflunomide: A Fluorescence Dynamics and Electronic Structure Study
Author:
Affiliation:
1. Department of Physics, Banaras Hindu University, Varanasi 221005, India
2. Physics Department, MMV, Banaras Hindu University, Varanasi 221005, India
Funder
Council of Scientific and Industrial Research
University Grants Commission
Department of Science and Technology, Ministry of Science and Technology
Alexander von Humboldt-Stiftung
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00088
Reference43 articles.
1. The Immunosuppressive Metabolite of Leflunomide Is a Potent Inhibitor of Human Dihydroorotate Dehydrogenase
2. Clinical Pharmacokinetics of Leflunomide
3. Leflunomide, a novel immunomodulating drug, inhibits homotypic adhesion of peripheral blood and synovial fluid mononuclear cells in rheumatoid arthritis
4. Leflunomide: mode of action in the treatment of rheumatoid arthritis
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