Rehabilitation After Stroke: Current State of the Science
Author:
Publisher
Springer Science and Business Media LLC
Subject
Clinical Neurology,General Neuroscience
Link
http://link.springer.com/content/pdf/10.1007/s11910-010-0091-9.pdf
Reference51 articles.
1. Taub E, Uswatte G: Constraint-induced movement therapy: bridging from the primate laboratory to the stroke rehabilitation laboratory. J Rehabil Med 2003, May(41 Suppl):34–40.
2. Wolf SL, Lecraw DE, Barton LA, Jann BB: Forced use of hemiplegic upper extremities to reverse the effect of learned nonuse among chronic stroke and head-injured patients. Exp Neurol 1989, 104:125–132.
3. Langhorne P, Coupar F, Pollock A: Motor recovery after stroke: a systematic review. Lancet Neurol 2009, 8(8):741–754.
4. •• Wolf SL, Winstein CJ, Miller JP, et al.: Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA 2006, 296(17):2095–2104. This is the largest (n = 222) RCT of CIMT, and because of its size and design, it continues to provide important longitudinal data on the efficacy of CIMT. The fact that its control group is not fully dose matched is an important lesson that will improve the design of future trials.
5. • Dromerick AW, Lang CE, Birkenmeier RL, et al.: Very Early Constraint-Induced Movement during Stroke Rehabilitation (VECTORS): a single-center RCT. Neurology 2009, 73(3):195–201. This trial demonstrated conclusively that just as for drugs, dose–response curves need to be developed for rehabilitation interventions. One cannot always assume more is better.
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