Differential signaling of Flt3 activating mutations in acute myeloid leukemia: a working model
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Drug Discovery,Biochemistry,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s13238-011-1020-7.pdf
Reference45 articles.
1. Chan, P.M., Ilangumaran, S., La Rose, J., Chakrabartty, A., and Rottapel, R. (2003). Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. Mol Cell Biol 23, 3067–3078.
2. Choudhary, C., Brandts, C., Schwable, J., Tickenbrock, L., Sargin, B., Ueker, A., Böhmer, F.D., Berdel, W.E., Müller-Tidow, C., and Serve, H. (2007). Activation mechanisms of STAT5 by oncogenic Flt3-ITD. Blood 110, 370–374.
3. Choudhary, C., Olsen, J.V., Brandts, C., Cox, J., Reddy, P.N., Böhmer, F.D., Gerke, V., Schmidt-Arras, D.E., Berdel, W.E., Müller-Tidow, C., et al. (2009). Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326–339.
4. Choudhary, C., Schwäble, J., Brandts, C., Tickenbrock, L., Sargin, B., Kindler, T., Fischer, T., Berdel, W.E., Müller-Tidow, C., and Serve, H. (2005). AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations. Blood 106, 265–273.
5. Dosil, M., Wang, S., and Lemischka, I.R. (1993). Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells. Mol Cell Biol 13, 6572–6585.
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