Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [11C]MK-8193-Reference-Cited by-同舟云学术

Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [11C]MK-8193

Published:2015-11-23 Issue:4 Volume:18 Page:579-587
ISSN:1536-1632
Container-title:Molecular Imaging and Biology
language:en
Short-container-title:Mol Imaging Biol

Author:

Hostetler Eric D.,Fan Hong,Joshi Aniket D.,Zeng Zhizhen,Eng Waisi,Gantert Liza,Holahan Marie,Meng Xianjun,Miller Patricia,O’Malley Stacey,Purcell Mona,Riffel Kerry,Salinas Cristian,Williams Mangay,Ma Bennett,Buist Nicole,Smith Sean M.,Coleman Paul J.,Cox Christopher D.,Flores Brock A.,Raheem Izzat T.,Cook Jacquelynn J.,Evelhoch Jeffrey L.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s11307-015-0910-0.pdf

Reference30 articles.

1. Bender AT, Beavo JA (2006) Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488–520

2. Coskran TM, Morton D, Menniti FS et al (2006) Immunohistochemical localization of phosphodiesterase 10A in multiple mammalian species. J Histochem Cytochem 54:1205–1213

3. Perez-Costas E, Melendez-Ferro M, Roberts RC (2010) Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. J Neurochem 113:287–302

4. Threlfell S, Sammut S, Menniti FS, Schmidt CJ, West AR (2009) Inhibition of phosphodiesterase 10A increases the responsiveness of striatal projection neurons to cortical stimulation. J Pharmacol Exp Ther 328:785–795

5. Nishi A, Snyder GL (2010) Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: biochemical and behavioral profiles of phosphodiesterase inhibition in dopaminergic neurotransmission. J Pharmacol Sci 114:6–16

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia;Journal of Medicinal Chemistry;2023-01-10

2. Advances in Cyclic Nucleotide Phosphodiesterase-Targeted PET Imaging and Drug Discovery;Journal of Medicinal Chemistry;2021-05-27

3. Medicinal chemistry strategies for the development of phosphodiesterase 10A (PDE10A) inhibitors - An update of recent progress;European Journal of Medicinal Chemistry;2021-03

4. New PET radiopharmaceuticals for imaging CNS diseases;Reference Module in Biomedical Sciences;2021

5. PET Radioligands for imaging of the PDE10A in human: current status;Neuroscience Letters;2019-01