ACT001 alleviates inflammation and pyroptosis through the PPAR-γ/NF-κB signaling pathway in LPS-induced alveolar macrophages-Reference-Cited by-同舟云学术

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ACT001 alleviates inflammation and pyroptosis through the PPAR-γ/NF-κB signaling pathway in LPS-induced alveolar macrophages

Published:2023-10-13 Issue: Volume: Page:
ISSN:1976-9571
Container-title:Genes & Genomics
language:en
Short-container-title:Genes Genom

Author:

Fu Qiang,Shen Na,Fang Tao,Zhang Hewei,Di Yanbo,Liu Xuan,Du Chao,Guo Jianshuang

Funder

Tianjin Science and Technology Program

Tianjin Municipal Health Commission

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s13258-023-01455-w.pdf

Reference34 articles.

1. Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A et al (2022) The dynamic interplay between AMPK/NFkappaB signaling and NLRP3 is a new therapeutic target in inflammation: emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury. Biomed Pharmacother 147:112628. https://doi.org/10.1016/j.biopha.2022.112628

2. Broz P, Pelegrin P, Shao F (2020) The gasdermins, a protein family executing cell death and inflammation. Nat Rev Immunol 20(3):143–157. https://doi.org/10.1038/s41577-019-0228-2

3. Burdette BE, Esparza AN, Zhu H, Wang S (2021) Gasdermin D in pyroptosis. Acta Pharm Sin B 11(9):2768–2782. https://doi.org/10.1016/j.apsb.2021.02.006

4. Cai L, Wu ZR, Cao L, Xu JD, Lu JL, Wang CD, Jin JH, Wu ZB, Su ZP (2022) ACT001 inhibits pituitary tumor growth by inducing autophagic cell death via MEK4/MAPK pathway. Acta Pharmacol Sin 43:2386–2396. https://doi.org/10.1038/s41401-021-00856-5

5. Cheng P, Li S, Chen H (2021) Macrophages in lung injury, repair, and fibrosis. Cells 10(2):436. https://doi.org/10.3390/cells10020436

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