Native Electrospray Mass Spectrometry of DNA G-Quadruplexes in Potassium Solution
Author:
Affiliation:
1. University Bordeaux, IECB, ARNA Laboratory, F-33600, Pessac, France
2. INSERM, U869, ARNA Laboratory, F-33000, Bordeaux, France
Publisher
American Chemical Society (ACS)
Subject
Spectroscopy,Structural Biology
Link
http://link.springer.com/content/pdf/10.1007/s13361-014-0890-3.pdf
Reference38 articles.
1. Rankin, S., Reszka, A.P., Huppert, J., Zloh, M., Parkinson, G.N., Todd, A.K., Ladame, S., Balasubramanian, S., Neidle, S.: Putative DNA quadruplex formation within the human c-kit oncogene. J. Am. Chem. Soc.127(6), 10584–10589 (2005)
2. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
3. G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription
4. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents
5. Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution
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