How many patients with severe sepsis are needed to confirm the efficacy of drotrecogin alfa activated? A Bayesian design
Author:
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00134-008-1159-8.pdf
Reference44 articles.
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3. Wiedermann CJ (2006) When a single pivotal trial should not be enough-the case of drotrecogin-alfa (activated). Intens Care Med 32:604
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5. Eichacker PQ, Danner RL, Suffredini AF, Cui X, Natanson C (2005) Reassessing recombinant human activated protein C for sepsis: time for a new randomized controlled trial. Crit Care Med 33:2426–2428
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