When a single pivotal trial should not be enough–the case of drotrecogin-alfa (activated)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00134-006-0086-9.pdf
Reference7 articles.
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3. Wiedermann CJ, Kaneider NC (2005) A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis. BMC Emerg Med 5:7
4. Friedrich JO (2006) Drotrecogin alfa (activated) in severe sepsis. N Engl J Med 354:94--95
5. Anonymous (2005) An unhealthy practice. Nature 437:1065--1066
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