Τhe story of sclerostin inhibition: the past, the present, and the future
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Endocrinology, Diabetes and Metabolism
Link
https://link.springer.com/content/pdf/10.1007/s42000-023-00521-y.pdf
Reference83 articles.
1. Anastasilakis AD, Polyzos SA, Toulis KA (2011) Role of wingless tail signaling pathway in osteoporosis: an update of current knowledge. Curr Opin Endocrinol Diabetes Obes 18(6):383–388. https://doi.org/10.1097/MED.0b013e32834afff2
2. Toulis KA, Anastasilakis AD, Polyzos SA, Makras P (2011) Targeting the osteoblast: approved and experimental anabolic agents for the treatment of osteoporosis. Hormones 10(3):174–195. https://doi.org/10.14310/horm.2002.1308
3. Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R (2006) Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res 21(11):1738–1749. https://doi.org/10.1359/jbmr.060810
4. Sutherland MK, Geoghegan JC, Yu C, Turcott E, Skonier JE, Winkler DG, Latham JA (2004) Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation. Bone 35(4):828–835. https://doi.org/10.1016/j.bone.2004.05.023
5. Wijenayaka AR, Kogawa M, Lim HP, Bonewald LF, Findlay DM, Atkins GJ (2011) Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway. PLoS ONE 6(10):e25900. https://doi.org/10.1371/journal.pone.0025900
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