Pharmacological characterization of N1-(2-methoxyphenyl)-N4-hexylpiperazine as a multi-target antagonist of α1A/α1D-adrenoceptors and 5-HT1A receptors that blocks prostate contraction and cell growth-Reference-Cited by-同舟云学术

Pharmacological characterization of N1-(2-methoxyphenyl)-N4-hexylpiperazine as a multi-target antagonist of α1A/α1D-adrenoceptors and 5-HT1A receptors that blocks prostate contraction and cell growth

Published:2013-11-10 Issue:3 Volume:387 Page:225-234
ISSN:0028-1298
Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
language:en
Short-container-title:Naunyn-Schmiedeberg's Arch Pharmacol

Author:

Chagas-Silva Fernanda,Nascimento-Viana Jéssica Barbosa,Romeiro Luiz Antonio S.,Barberato Luana C.,Noël François,Silva Claudia Lucia Martins

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00210-013-0935-3.pdf

Reference61 articles.

1. Anglin IE, Glassman DT, Kyprianou N (2002) Induction of prostate apoptosis by α1-adrenoceptor antagonists: mechanistic significance of the quinazoline component. Prostate Cancer Prostatic Dis 5:88–95

2. Assié MB, Cosi C, Koek W (1999) Correlation between low/high affinity ratios for 5-HT(1A) receptors and intrinsic activity. Eur J Pharmacol 386:97–103

3. Barnes NM, Sharp T (1999) A review of central 5-HT receptors and their function. Neuropharmacology 38:1083–1152

4. Bautista DL, Morris DH, Stein L, Asher W, Hammitt T (2006) A two model receptor system of the alpha1D adrenergic receptor to describe interactions with epinephrine and BMY7378. J Chem Inf Model 46:334–344

5. Borbe OH, Metzenauer P, Szelenyi I (1991) 5-HT1A-agonistic properties of naftopidil, a novel antihypertensive drug. Eur J Pharmacol 205:105–107

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